Your Name: Jyoti Bakshi

Theme: Goodpastures Syndrome

 

OPTION LIST

 

A

SKIN

I

HLA-DR2

B

SMOOTH LINEAR PATTERN

J

GLOMERULAR BASEMENT MEMBRANE

C

BLOOD VESSELS

K

TYPE II COLLAGEN

D

CICLOSPORIN

L

MESANGIUM

E

PLASMAPHERESIS

M

PREDINSOLONE

F

TYPE IV COLLAGEN

N

LUNG

G

TYPE 11 HYPERSENSITIVITY

O

HLA-DR3

H

LUMPY-BUMPY PATTERN

P

ANTI-NEUTROPHIL CYTOPLASMIC ANTIBODIES

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

IN GOODPASTURES SYNDROME:

 

1. What is the specific auto-antigen that is the target of the immune system?

 

 

2. The pattern of anti-body deposition in the Glomerular Basement membrane is typically described as what?

 

 

3. Name the drug most likely used in the treatment of this disease.

 

 

4. Immune damage may be associated with the kidney and commonly which other tissue ?

 

 

5.  The disease is strongly associated with which allelle?

 

 

ANSWERS

1. F

2. B

3. M

4. N

5. I